https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 What is the “optimal” target mismatch criteria for acute ischemic stroke? https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43675 P = 0.005), whereas there was no such association between reperfusion and an excellent outcome with any of the CCM criteria (all p > 0.05). Notably, in IVT-LVO cohort, 58.2% of the PIM-DT positive patients achieved an excellent outcome compared with 31.0% in non-mismatch patients following successful recanalization (P = 0.006).]]> Wed 28 Sep 2022 14:35:18 AEST ]]> Exploring the relationship between ischemic core volume and clinical outcomes after thrombectomy or thrombolysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42116 p < 0.001). The group with a baseline core <30 mL contained mostly patients with distal M1 or M2 occlusions, and good collaterals ( p = 0.01). In patients with a baseline ischemic core volume >30 mL (internal carotid artery and mostly proximal M1 occlusions), EVT-R increased the odds of patients achieving an excellent clinical outcome (day 90 mRS 0–1 odds ratio 1.61, p < 0.001) and there was increased symptomatic intracranial hemorrhage in the IVT-R group with core >30 mL (20% vs 3% in EVT-R, p = 0.008). Conclusion: From this observational cohort, LVO patients with larger baseline ischemic cores and proximal LVO, with poorer collaterals, clearly benefited from EVT-R compared to IVT-R alone. However, for distal LVO patients, with smaller ischemic cores and better collaterals, EVT-R was associated with a lower odds of favorable outcome compared to IVT-R alone.]]> Thu 25 Aug 2022 11:08:38 AEST ]]> An online cross-sectional survey of the health risk behaviours among informal caregivers https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38574 Mon 29 Jan 2024 17:57:08 AEDT ]]> Intracranial pressure elevation post-stroke: Mechanisms and consequences https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:53077 Fri 17 Nov 2023 12:03:34 AEDT ]]>